The pathology of osteoarthritis is extremely complex and multifactorial.
Recent technological advances have allowed the identification of specific genes and
genetic alterations which have helped to elucidate some intricacies involved in the
molecular basis of disease development and progression. Known factors and key recent
discoveries in pathogenesis, plus typical gross and histologic pathologic findings are
described in this chapter.
Keywords: Degenerative joint disease, Gene, Genetic, Gross, Histology,
Microscopic, Molecular, Morphology, Osteoarthritis, Pathology.
