Title:Pattern and Correlates of Hypomagnesemia Among Subset of Diabetes Mellitus
Volume: 16
Issue: 4
Author(s): Ihsan Salah Rabeea*, Karrar Al-Gburi, Ihsan Adnan, Bilal Hasan, Massa Mohammed and Mariam Mohammed
Affiliation:
- Department of Clinical Pharmacy, University of Kufa, Faculty of Pharmacy, Najaf Governorate,Iraq
Keywords:
Hypomagnesemia, diabetes mellitus, magnesium ion, patients, metformin, serum creatinine, standard deviation.
Abstract:
Background: Nowadays, there is an accumulated data about the relation between hypomagnesemia
(low Serum Mg level < 0.7 mmol/l) and diabetes.
Objective: In this study, we aimed to determine the prevalence of hypomagnesemia in a carefully diagnosed
diabetes patients and to show how some factors could contribute to the prevalence of low serum
Mg level among the population under study.
Methods: In short, 62 patients of both type 1 and 2, who attended AL-Sadir medical city/ diabetes and
endocrinology centre during the period of the study were included in the study. A detailed history was
taken and participants were informed verbally about the procedure of this study. Serum magnesium and
creatinine were measured using standardized methods.
Results: The overall prevalence of the hypomagnesemia, among diabetic population involved in this
study, was 29.03 % and it was nearly similar in male (29.41 %) and female (28.57 %). The means(SD)
of serum Mg level were similar in type 1 and type 2 diabetic patients. Other difference in prevalence
among other characteristics has been reported. Within all participants, gender (r = -0.02), fasting blood
glucose (r = -0.514) and metformin use (r = -0.014) were negatively correlated with serum Mg level, in
contrast to other variables, which were positively correlated. While among type 1 DM, age (r= 0.193),
serum creatinine (r= 0.031) and insulin use (r= 0.217) were positively correlated with serum Mg level.
In contrast, others were negatively correlated. In type 2 DM, age (r = -0.283) and fasting blood glucose
(r = -0.496) were negatively correlated with serum Mg level. On the other hand, other variables were
positively correlated with serum Mg level.
Conclusion: Hypomagnesemia prevalence was detected in nearly one-third of the diabetic population,
which is quite high prevalence. Some factors have shown to play an essential role in this prevalence. A
large study is warranted to address this issue.
