Title: Tumor Escape from Immune Response: Mechanisms and Targets of Activity
Volume: 4
Issue: 7
Author(s): Dmitry Gabrilovich and Vladimir Pisarev
Affiliation:
Keywords:
Immune, tumor cells, antigen-presenting cells
Abstract: Immune system plays an important role in control of tumor progression. Effective antitumor immune response depends on close interaction of several elements of immune system. They include antigen-presenting cells, different subsets of T cells, B cells and NK cells. However, tumor cells developed a number of mechanisms to escape recognition and elimination by immune system. In this review we will discuss these mechanisms and address possible approaches to correct them.
