Title:Advances in the Use of Multifunctional Mesoporous Silica Nanoparticles and Related Nanomaterials as Carriers for the Cancer Treatment
Volume: 19
Issue: 2
Author(s): Chunyu Song, Xinghua Wang, Yujun Wang, Hongbo Yu, Yali Cui and Tengchuang Ma*
Affiliation:
- Department of Nuclear Medicine, China Medical University, Harbin,China
Keywords:
Mesoporous silica nanoparticles, drug delivery system, cancer treatment, targeted, nanocarriers, clinical trials.
Abstract: Background: In recent years, there has been an unprecedented expansion in the field of nanomedicine
with the development of new nanoparticles for the diagnosis and treatment of cancer. It is also known that the use of
nanocarriers as drug delivery systems for therapeutic or imaging agents can improve the pharmacological properties
of ordinarily used compounds in cancer diagnosis and treatment.
Objective: Advances in the surface regulating of nanoparticles to accommodate targeting ligands turned nanocarriers
attractive candidates for future impact involving targeted drug delivery. Although not targeted, several nanocarriers
have been approved for clinical use and they are currently used to treat or diagnose various kinds of cancers. Furthermore,
there are several formulations, which are now in various stages of clinical trials than also can combine
with thermal treatment.
Conclusion: This review examined some mesoporous silica nanoparticles and related nanomaterials and discussed
the advantages of using nanocarriers in cancer therapy.
