Title:An Uncommon Case of Symptomatic Multiple Meningiomas with Bilateral Compressive Optic Neuropathy Rapidly Induced under Cyprotero ne Acetate Treatment
Volume: 12
Issue: 2
Author(s): Chafik Keilani*Samir Abada
Affiliation:
- CHNO des quinze-vingts, Faculty of Medicine Pierre et Marie Curie (Paris VI), 28 Rue de Charenton, 75 571 Paris,France
Keywords:
Papilledema, bilateral optic nerve compression, multiple meningiomas, cyproterone acetate, pharmacovigilance,
exposure time.
Abstract: Introduction: Multiple meningiomas growth in patients under cyproterone acetate (CPA) is
now well known. However, time between initial CPA intake and diagnosis remains unclear.
Methods: The exposure time differs in each reported case: from 2 to 10 years. We present the case of
an old man with acute visual impairment caused by an unusual bilateral optic nerve compression by
three likely planum sphenoidale meningiomas rapidly induced by the admistration of CPA for
prostatic adenocarinoma.
Results and Conclusion: This case is the first reported with a short exposure time (7 months) to CPA
treatment before diagnosis of multiple meningiomas and stabilization on clinical follow-up after CPA
treatment discontinuation.
