Title:A Review on the Sex Differences in Organ and System Pathology with Alcohol Drinking
Volume: 9
Issue: 2
Author(s): Vatsalya Vatsalya, Hammad Bin Liaquat, Kuldeep Ghosh, Sri Prakash Mokshagundam and Craig J McClain*
Affiliation:
- Department of Medicine, Pharmacology and Toxicology, University of Louisville School of Medicine, 505 S. Hancock St. CTR Room 503, Louisville KY 40202,United States
Keywords:
Alcohol, organ injury, pharmacology, sex difference, pathology, addiction.
Abstract: Hazardous consequences of alcohol consumption adversely influence overall health, specifically
physical and mental health. Differences in alcohol consumption and manifestations in pathology
have been observed between males and females, however research on understanding these
differences is limited. Negative consequences of alcohol consumption have now been studied including
sex as a significant factor. Some studies have shown differences in the severity of consequences
of alcohol consumption between the sexes, both in the mental consequences and changes/
injury in various organ systems. Over time, reports in females on both the dynamics of drinking and
on the hazardous consequences of alcohol consumption have grown, primarily because of more
awareness, better observation, and the inclusion of sex as a factor in scientific investigations. This
paper reviews role of sex differences in pathophysiological and behavioral consequences of alcohol
drinking.
