Title:Isolated Perioperative Hypertension: Clinical Implications & Contemporary Treatment Strategies
Volume: 10
Issue: 1
Author(s): Gregory M. Dodson, William E. Bentley IV, Ahmed Awad, Muhammed Muntazar and Michael E. Goldberg
Affiliation:
Keywords:
Alpha-2 agonists, anesthesia, anti-hypertensive, beta-blockers, blood pressure, calcium channel blockers, nitrates.
Abstract: Perioperative hypertension has been shown to be a risk factor for the development of perioperative morbidity
and mortality. The time spent outside acceptable blood pressure ranges, in a state of hypertension or hypotension, is
correlated with the incidence of stroke, acute coronary syndrome, renal dysfunction, and death. The ideal perioperative
treatment of hypertension would include an easily titratable agent, with fast onset and offset and minimal side effects.
Several medication classes are routinely used in the operating room, including, but not limited to, beta-blockers, calcium
channel blockers, nitrates, and angiotensin-converting enzyme (ACE) inhibitors.Proper treatment of chronic hypertension
and continuation of chronic anti-hypertensive medications in the perioperative period has been demonstrated to improve
patient outcomes. This review article will outline the importance of perioperative blood pressure management, the
treatment pitfalls, and the novel medications being used in the perioperative setting.
