Title:Synthesis of 2-Amino-4H-Chromen-4-yl Phosphonats via C-P Bond Formation Catalyzed by Nano-Rods ZnO Under Solvent-Free Condition
Volume: 17
Issue: 1
Author(s): Mona Hosseini-Sarvari and Atefeh Roosta
Affiliation:
Keywords:
2-amino-4H-chromen-4-yl phosphonate, nano rods ZnO, solvent-free, three-component reactions.
Abstract: One-pot, three-component reactions of structurally diverse salicylaldehydes with malononitrile (or
ethylcyanoacetate) and diethyl (or dimethyl) phosphate are carried out in the presence of nano-rods ZnO as an efficient
catalyst for the synthesis of biologically interesting 2-amino-4H-chromen-4-yl phosphonate derivatives. The value of this
method lies in its mild and environmentally benign reaction, simple procedure, good yields, and ease of handling.