Title:Hypertension in Children with Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Volume: 9
Issue: 1
Author(s): Melissa A. Cadnapaphornchai
Affiliation:
Keywords:
Hypertension, Pediatric, ADPKD
Abstract: Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary renal disease,
affecting 1 in 1000 individuals. Previously termed “adult polycystic kidney disease”, ADPKD is now known to have
important clinical manifestations beginning early in life and even in utero. Hypertension is an important risk factor for
progressive renal and cardiovascular disease in children with ADPKD and may signify irremediable organ injury. The
purpose of this article is to review current knowledge and treatment strategies in hypertension associated with pediatric
ADPKD.