Title: Dual Action-Based Approaches to Antibacterial Agents
Volume: 14
Issue: 13
Author(s): John B. Bremner, Joseph I. Ambrus and Siritron Samosorn
Affiliation:
Keywords:
Dual action antibacterials, bacterial resistance, dual action drugs, dual action prodrugs
Abstract: This review collates and analyses recent work done on dual action approaches to tackling the mounting health problem of resistance by human pathogenic bacteria to antibacterial agents. In particular the areas reviewed include the use of two drugs in combination, dual action prodrugs, and dual action drugs (or hybrid drugs)