Title:Nano-based Herbal Medicine: A New Candidate for Prostate Cancer
Treatment?
Volume: 10
Issue: 7
Author(s): Tayebe Pouryousefi-koodehi, Mohammad Saeed Kahrizi, Hossein Roghani-Shahraki, Fatemeh Rezaei-Tazangi, Reza Arefnezhad*Hossein Motedayyen*
Affiliation:
- Coenzyme R Research
Institute, Tehran, Iran
- Autoimmune Diseases Research Center, Shahid Beheshti Hospital, Kashan University of Medical
Sciences, Kashan, Iran
Keywords:
Curcumin, quercetin, resveratrol, herbal remedy, nanomaterials, prostate cancer (PCa).
Abstract:
Background: Prostate cancer (PCa) is known as the fifth reason for cancer-related
deaths and involves a considerable population of men globally. In PCa, pluriform neoplasm with
different cancer patterns is formed. Metastases have a substantial role in disease mortality, and
lung, liver, and bone are among the common organs for metastasis. In spite of multiple attempts by
researchers, it has not been recommended a safe and suitable approach against PCa so far.
Results: Fortunately, herbal remedies have opened a novel window in order to treat several cancers,
such as PCa; however, there are some barriers regarding this curative method, like low bioavailability
and absorption and low water solubility. On the contrary, some nano-based formulations
have revealed a potential ability to overcome these limitations, and it seems that the co-use of
herbal products and nanoformulations provides a good opportunity for treating PCa.
Conclusion: In this study, we argued about the therapeutic aspects of some nanoformulations of
popular herbal products, such as curcumin, quercetin, and resveratrol, against PCa.
