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Current Drug Therapy

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ISSN (Print): 1574-8855
ISSN (Online): 2212-3903

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Review Article

Biodegradable Polymeric Microspheres as Drug Carriers for Anti- Microbial Agent

Author(s): Nidhi Bansal, Komal Rao, Nikita Yadav and Neha Minocha*

Volume 19, Issue 1, 2024

Published on: 06 June, 2023

Page: [49 - 59] Pages: 11

DOI: 10.2174/1574885518666230530095329

Price: $65

Abstract

Introduction: Microspheres, the novel drug delivery system that offers therapeutic alternatives to single-unit dosage forms, both conventional and quick release. Microspheres are solid microspheres having a diameter of 1-1000 μm. Microspheres can be made utilising various procedures that vary in their effectiveness and dosage form administration when compared to standard dosage forms.

Background: The idea of targeted drug delivery is to concentrate the treatment in the target tissues while lowering the relative concentration of the drug in the non-target tissues. As a result, the medication is concentrated at the desired location. Thus, the medication has no effect on the tissues nearby. Therefore, by combining the drug with carrier particle like microspheres, nanoparticles, liposomes, niosomes, etc., that regulates the release and absorption characteristics of the drug, carrier technology offers an intelligent way for drug delivery.

Results: Microspheres are naturally biodegradable materials made of proteins or synthetic polymers that flow freely. Its formulation is approachable, maintaining the desired concentration at the site of interest without unfavorable effects and reliably delivering the drug to the target site with specificity.

Conclusion: Microspheres attracted a lot of interest for their sustained release as well as their ability to direct anti-cancer medications to the tumour using biodegradable polymers. Due to this, future drug delivery systems for innovative medications will heavily rely on microspheres.

Keywords: Microspheres, cross-linking, encapsulation, therapeutic, controlled-release, liposomes.

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