Title:Pathophysiology of Cardiac Cell Injury in Post-COVID-19 Syndrome
Volume: 4
Author(s): Basheer Abdullah Marzoog*
Affiliation:
- National Research Mordovia State University, Bolshevitskaya Street 68, Saransk, Rep. Mordovia 430005, Mordovia Republic, Saransk, Russia
Keywords:
COVID-19, SARS-coV-2, Pathogenesis, Post-COVID syndrome, Cardiovascular system, ACE, RAAS, Cardiology, Pathophysiology.
Abstract: Recently, the scientific community has realized that COVID-19 effects are not limited to the acute period of infection but continue beyond that to
cause more prolonged pathological changes. Post-COVID syndrome is a novel concept that describes the sequelae/persistent pathophysiological
changes of post-COVID-19 infection. The current hypothesis suggests the involvement of severe acute respiratory syndrome coronavirus 2 (SARSCoV-
2) in cardiac arrhythmias, coronary artery aneurism, acute renal injury, central nervous system degenerative diseases, vascular endothelial cell
dysfunction, and pulmonary dyspnea, as well as fibrotic lung damage. Therefore, COVID-19 has been identified as a poly-syndromic and polysystemic
inflammatory disease. Post-COVID extrapulmonary complications have been observed in approximately 85% of hospitalized COVID-19
survivors and 35% of COVID-19 outpatients. Furthermore, 25% of hospitalised COVID-19 survivors developed myocardiopathy.
