Title:Hybrids Diazine: Recent Advancements in Modern Antimicrobial
Therapy
Volume: 31
Issue: 19
关键词:
杂氮杂氮,抗菌,吡嗪,嘧啶,吡嗪,融合嘧啶。
摘要: Nowadays, antimicrobial therapies have become a very challenging issue because
of a large diversity of reasons such as antimicrobial resistance, over consumption
and misuse of antimicrobial agents, etc. A modern, actual and very useful approach in antimicrobial
therapy is represented by the use of hybrid drugs, especially combined five
and six-membered ring azaheterocycles. In this review, we present an overview of the recent
advanced data from the last five years in the field of hybrid diazine compounds with
antimicrobial activity. In this respect, we highlight here essential data concerning the synthesis
and antimicrobial activity of the main classes of diazine hybrids: pyridazine, pyrimidine,
pyrazine, and their fused derivatives.