Title:The Effects of Different Temperaments on Vascular Parameters: A Pilot
Crossover Randomized Controlled Trial
Volume: 14
Issue: 1
Author(s): Mohsen Zakerian, Fatemeh Roudi, Reza Rezvani, Lida Jarahi, Mahdi Yousefi, Majid Anoushirvani, Amirhossein Sahebkar*Malihe Motavasselian*
Affiliation:
- Biotechnology Research Center, Pharmaceutical Technology Institute,
Mashhad University of Medical Sciences, Mashhad, Iran
- Applied Biomedical Research Center, Mashhad
University of Medical Sciences, Mashhad, Iran
- Department of Persian Medicine, School of Persian and Complementary Medicine, Mashhad University of
Medical Sciences, Mashhad, Iran
Keywords:
Temperament, arterial stiffness, complementary medicine, vascular parameters, warm or cold temperament, cardiovascular.
Abstract:
Background: According to the Persian Medicine (PM) point of view, the function of
the cardiovascular system and the risk of cardiovascular events would be different between subjects
having warm and cold temperaments. Moreover, different foods in terms of temperament
may lead to different acute and chronic effects on the body.
Objective: We investigated the postprandial effects of PM-based warm and cold test meals on arterial
stiffness indices in healthy men with warm and cold temperaments.
Methods: Twenty-one eligible warm or cold temperament subjects with a similar range of age,
weight, and heights were enrolled in this pilot cross-over randomized controlled trial study during
February- October 2020. Two test meals (cold and warm PM-based temperament foods)
were designed as different interventions. Pulse wave velocity (PWV) and pulse wave analysis
(PWA) was obtained at the baseline state (following 12 hours fasting), 0.5, 2, and 4 hours after
the test meal consumption during each test day.
Results: Warm temperament participants had higher values of lean body mass, total body water,
and protein content (P = 0.03, 0.02, and 0.02, respectively). Cold temperament individuals had
higher aortic heart rate (HR) following 12 hours of fasting (P <0.001). On the other hand, the
augmentation pressure (AP) of warm temperament individuals was higher than the colds (
P = < 0.001).
Conclusion: According to the results of the present study, although warm temperament individuals
could have higher arterial stiffness at the fasting state, arterial stiffness indices had a greater
reduction following warm-temperament meal intake compared to cold-temperament meal.
