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Current Drug Delivery

Editor-in-Chief

ISSN (Print): 1567-2018
ISSN (Online): 1875-5704

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Inhaled Lipid Nanoparticles: A Feasible Tool for a Challenging Route

Author(s): Eliana Leo* and Eleonora Maretti

Volume 21, Issue 3, 2024

Published on: 21 February, 2023

Page: [309 - 311] Pages: 3

DOI: 10.2174/1567201820666230210161253

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[1]
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[2]
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[5]
Truzzi, E.; Nascimento, T.L.; Iannuccelli, V.; Costantino, L.; Lima, E.M.; Leo, E.; Siligardi, C.; Gualtieri, M.L.; Maretti, E. In vivo biodistribution of respirable solid lipid nanoparticles surface-decorated with a mannose-based surfactant: a promising tool for pulmonary tuberculosis treatment? Nanomaterials (Basel), 2020, 10(3), 568.
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[6]
Truzzi, E.; Meneghetti, F.; Mori, M.; Costantino, L.; Iannuccelli, V.; Maretti, E.; Domenici, F.; Castellano, C.; Rogers, S.; Capocefalo, A.; Leo, E. Drugs/lamellae interface influences the inner structure of double-loaded liposomes for inhaled anti-TB therapy: An in-depth small-angle neutron scattering investigation. J. Colloid Interface Sci., 2019, 541, 399-406.
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Herman, L.; De Smedt, S.C.; Raemdonck, K. Pulmonary surfactant as a versatile biomaterial to fight COVID-19. J. Control. Release, 2022, 342, 170-188.
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[14]
Maretti, E.; Rustichelli, C.; Lassinantti Gualtieri, M.; Costantino, L.; Siligardi, C.; Miselli, P.; Buttini, F.; Montecchi, M.; Leo, E.; Truzzi, E.; Iannuccelli, V. The impact of lipid corona on rifampicin intramacrophagic transport using inhaled solid lipid nanoparticles surface-decorated with a mannosylated surfactant. Pharmaceutics, 2019, 11(10), 508.
[http://dx.doi.org/10.3390/pharmaceutics11100508] [PMID: 31581554]
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Liu, Q.; Guan, J.; Song, R.; Zhang, X.; Mao, S. Physicochemical properties of nanoparticles affecting their fate and the physiological function of pulmonary surfactants. Acta Biomater., 2022, 140, 76-87.
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Sawarkar, S.; Prabhu, P.; Fernandes, T.; Damani, M.; Chaubey, P.; Narayanan, S. 2 Receptor specific ligand conjugated nanocarriers: an effective strategy for targeted therapy of tuberculosis. Curr. Drug Deliv., 2022, 19(8), 830-845.
[http://dx.doi.org/10.2174/1567201819666211216141942] [PMID: 34915835]
[17]
Bain, C.C.; Rossi, A.G.; Lucas, C.D. Pulmonary macrophages and SARS-Cov2 infection. Int. Rev. Cell Mol. Biol., 2022, 367, 1-28.
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[18]
Schwab, C.; Domke, L.M.; Rose, F.; Hausser, I.; Schirmacher, P.; Longerich, T. Cell tropism and viral clearance during SARS-CoV-2 lung infection. Pathol. Res. Pract., 2022, 236, 154000.
[http://dx.doi.org/10.1016/j.prp.2022.154000] [PMID: 35797854]
[19]
Hussain, A.; Singh, S.; Das, S.S.; Anjireddy, K.; Karpagam, S.; Shakeel, F. Nanomedicines as drug delivery carriers of anti-tubercular drugs: from pathogenesis to infection control. Curr. Drug Deliv., 2019, 16(5), 400-429.
[http://dx.doi.org/10.2174/1567201816666190201144815] [PMID: 30714523]
[20]
Lynch, H.F.; Robertson, C.T. Challenges in confirming drug effectiveness after early approval. Science, 2021, 374(6572), 1205-1207.
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[21]
Maretti, E.; Costantino, L.; Buttini, F.; Rustichelli, C.; Leo, E.; Truzzi, E.; Iannuccelli, V. Newly synthesized surfactants for surface mannosylation of respirable SLN assemblies to target macrophages in tuberculosis therapy. Drug Deliv. Transl. Res., 2019, 9(1), 298-310.
[http://dx.doi.org/10.1007/s13346-018-00607-w] [PMID: 30484257]
[22]
Dalpiaz, A.; Fogagnolo, M.; Ferraro, L.; Beggiato, S.; Hanuskova, M.; Maretti, E.; Sacchetti, F.; Leo, E.; Pavan, B. Bile salt-coating modulates the macrophage uptake of nanocores constituted by a zidovudine prodrug and enhances its nose-to-brain delivery. Eur. J. Pharm. Biopharm., 2019, 144, 91-100.
[http://dx.doi.org/10.1016/j.ejpb.2019.09.008] [PMID: 31521715]

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