Login Register Cart 0
Generic placeholder image

Pharmaceutical Nanotechnology

Editor-in-Chief

ISSN (Print): 2211-7385
ISSN (Online): 2211-7393

Back
Journal Home About Journal Editorial Board Journal Insight Current Issue Volumes/Issues
Subscribe
Commentary

Advances and Perspectives of Pharmaceutical Nanotechnology in mRNA Therapy

Author(s): Hui Cheng and Zongjin Li*

Volume 10, Issue 5, 2022

Published on: 06 October, 2022

Page: [328 - 333] Pages: 6

DOI: 10.2174/2211738510666220825145124

Open Access Journals Promotions 2
« Previous Next »
Verbeke R.; Lentacker I.; De Smedt S.C.; Dewitte H.; The dawn of mRNA vaccines: The COVID-19 case. J Control Release 2021,333,511-520 10.1016/j.jconrel.2021.03.043 33798667 Tenchov R.; Bird R.; Curtze A.E.; Zhou Q.; Lipid nanoparticles-from liposomes to mRNA vaccine delivery, a landscape of research diversity and advancement. ACS Nano 2021,15,16982-17015 10.1021/acsnano.1c04996 34181394 Bhattacharya M.; Sharma A.R.; Ghosh P.; Bioengineering of novel non-replicating mRNA (NRM) and self-amplifying mRNA (SAM) vac-cine candidates against SARS-CoV-2 using immunoinformatics approach. Mol Biotechnol 2022,64(5),510-525 10.1007/s12033-021-00432-6 34981440 Weng Y.; Li C.; Yang T.; The challenge and prospect of mRNA therapeutics landscape. Biotechnol Adv 2020,40,107534 10.1016/j.biotechadv.2020.107534 32088327 Gao M.; Zhang Q.; Feng X.H.; Liu J.; Synthetic modified messenger RNA for therapeutic applications. Acta Biomater 2021,131,1-15 10.1016/j.actbio.2021.06.020 34133982 Boo S.H.; Kim Y.K.; The emerging role of RNA modifications in the regulation of mRNA stability. Exp Mol Med 2020,52(3),400-408 10.1038/s12276-020-0407-z 32210357 Chaudhary N.; Weissman D.; Whitehead K.A.; mRNA vaccines for infectious diseases: Principles, delivery and clinical translation. Nat Rev Drug Discov 2021,20(11),817-838 10.1038/s41573-021-00283-5 34433919 Eygeris Y.; Gupta M.; Kim J.; Sahay G.; Chemistry of lipid nanoparticles for RNA delivery. Acc Chem Res 2022,55(1),2-12 10.1021/acs.accounts.1c00544 34850635 Ryals R.C.; Patel S.; Acosta C.; McKinney M.; Pennesi M.E.; Sahay G.; The effects of PEGylation on LNP based mRNA delivery to the eye. PLoS One 2020,15(10),e0241006 10.1371/journal.pone.0241006 33119640 Hassett K.J.; Higgins J.; Woods A.; Impact of lipid nanoparticle size on mRNA vaccine immunogenicity. J Control Release 2021,335,237-246 10.1016/j.jconrel.2021.05.021 34019945 Chen S.; Tam Y.Y.C.; Lin P.J.C.; Sung M.M.H.; Tam Y.K.; Cullis P.R.; Influence of particle size on the in vivo potency of lipid nanoparticle formula-tions of siRNA. J Control Release 2016,235,236-244 10.1016/j.jconrel.2016.05.059 27238441 Cabral H.; Matsumoto Y.; Mizuno K.; Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size. Nat Nanotechnol 2011,6(12),815-823 10.1038/nnano.2011.166 22020122 Kim M.; Jeong M.; Hur S.; Engineered ionizable lipid nanoparticles for targeted delivery of RNA therapeutics into different types of cells in the liver. Sci Adv 2021,7(9),eabf4398 10.1126/sciadv.abf4398 33637537 Hersh A.M.; Alomari S.; Tyler B.M.; Crossing the blood-brain barrier: Advances in nanoparticle technology for drug delivery in neuro-oncology. Int J Mol Sci 2022,23(8),4153 10.3390/ijms23084153 35456971 Renukaradhya G.J.; Narasimhan B.; Mallapragada S.K.; Respiratory nanoparticle-based vaccines and challenges associated with animal models and translation. J Control Release 2015,219,622-631 10.1016/j.jconrel.2015.09.047 26410807 Kowalski P.S.; Rudra A.; Miao L.; Anderson D.G.; Delivering the messenger: Advances in technologies for therapeutic mRNA delivery. Mol Ther 2019,27(4),710-728 10.1016/j.ymthe.2019.02.012 30846391 Park J.W.; Lagniton P.N.P.; Liu Y.; Xu R.H.; mRNA vaccines for COVID-19: What, why and how. Int J Biol Sci 2021,17(6),1446-1460 10.7150/ijbs.59233 33907508 Gaviria M.; Kilic B.; A network analysis of COVID-19 mRNA vaccine patents. Nat Biotechnol 2021,39(5),546-548 10.1038/s41587-021-00912-9 33981074 Vu M.N.; Kelly H.G.; Kent S.J.; Wheatley A.K.; Current and future nanoparticle vaccines for COVID-19. EBioMedicine 2021,74,103699 10.1016/j.ebiom.2021.103699 34801965 Wang L.; Wang Y.; Li Z.; Nanoparticle-based tumor theranostics with molecular imaging. Curr Pharm Biotechnol 2013,14(7),683-692 10.2174/1389201014666131226111248 24372235 Berraondo P.; Martini P.G.V.; Avila M.A.; Fontanellas A.; Messenger RNA therapy for rare genetic metabolic diseases. Gut 2019,68(7),1323-1330 10.1136/gutjnl-2019-318269 30796097 Damase T.R.; Sukhovershin R.; Boada C.; Taraballi F.; Pettigrew R.I.; Cooke J.P.; The limitless future of RNA therapeutics. Front Bioeng Biotechnol 2021,9,628137 10.3389/fbioe.2021.628137 33816449 Chabanovska O.; Galow A.M.; David R.; Lemcke H.; mRNA - A game changer in regenerative medicine, cell-based therapy and reprogramming strategies. Adv Drug Deliv Rev 2021,179,114002 10.1016/j.addr.2021.114002 34653534 Scheideler M.; Vidakovic I.; Prassl R.; Lipid nanocarriers for microRNA delivery. Chem Phys Lipids 2020,226,104837 10.1016/j.chemphyslip.2019.104837 31689410 Inoue J.; Inazawa J.; Cancer-associated miRNAs and their therapeutic potential. J Hum Genet 2021,66(9),937-945 10.1038/s10038-021-00938-6 34088973 Rupaimoole R.; Slack F.J.; MicroRNA therapeutics: Towards a new era for the management of cancer and other diseases. Nat Rev Drug Discov 2017,16(3),203-222 10.1038/nrd.2016.246 28209991 Deng S.; Zhao Q.; Zhen L.; Neonatal heart-enriched miR-708 promotes proliferation and stress resistance of cardiomyocytes in rodents. Theranostics 2017,7(7),1953-1965 10.7150/thno.16478 28638481 Peng B.; Chen Y.; Leong K.W.; MicroRNA delivery for regenerative medicine. Adv Drug Deliv Rev 2015,88,108-122 10.1016/j.addr.2015.05.014 26024978 Ghatak S.; Li J.; Chan Y.C.; AntihypoxamiR functionalized gramicidin lipid nanoparticles rescue against ischemic memory improving cutaneous wound healing. Nanomedicine 2016,12(7),1827-1831 10.1016/j.nano.2016.03.004 27033464 Bejerano T.; Etzion S.; Elyagon S.; Etzion Y.; Cohen S.; Nanoparticle delivery of miRNA-21 mimic to cardiac macrophages improves myocar-dial remodeling after myocardial infarction. Nano Lett 2018,18(9),5885-5891 10.1021/acs.nanolett.8b02578 30141949 Takeda Y.S.; Wang M.; Deng P.; Xu Q.; Synthetic bioreducible lipid-based nanoparticles for miRNA delivery to mesenchymal stem cells to induce neuronal differentiation. Bioeng Transl Med 2016,1(2),160-167 10.1002/btm2.10021 29313011 Lee S.W.L.; Paoletti C.; Campisi M.; MicroRNA delivery through nanoparticles. J Control Release 2019,313,80-95 10.1016/j.jconrel.2019.10.007 31622695 Tabatabaei S.N.; Derbali R.M.; Yang C.; Co-delivery of miR-181a and melphalan by lipid nanoparticles for treatment of seeded retinoblas-toma. J Control Release 2019,298,177-185 10.1016/j.jconrel.2019.02.014 30776396 Yuan H.; Peng Y.M.; Long Z.Y.; Wu S.X.; Zhou Y.F.; Lipid nanoparticles co-loaded with miRNA-22 and methotrexate for enhanced anti-inflammatory response in rheumatoid arthritis. Biosci Rep 2020,BSR20201735 10.1042/BSR20201735 32808648 Bhardwaj P.; Bhatia E.; Sharma S.; Ahamad N.; Banerjee R.; Advancements in prophylactic and therapeutic nanovaccines. Acta Biomater 2020,108,1-21 10.1016/j.actbio.2020.03.020 32268235 Schoenmaker L.; Witzigmann D.; Kulkarni J.A.; mRNA-lipid nanoparticle COVID-19 vaccines: Structure and stability. Int J Pharm 2021,601,120586 10.1016/j.ijpharm.2021.120586 33839230 Blumenthal K.G.; Phadke N.A.; Bates D.W.; Safety surveillance of COVID-19 mRNA vaccines through the vaccine safety datalink. JAMA 2021,326(14),1375-1377 10.1001/jama.2021.14808 34477809 Duan Y.; Wang S.; Zhang Q.; Gao W.; Zhang L.; Nanoparticle approaches against SARS-CoV-2 infection. Curr Opin Solid State Mater Sci 2021,25(6),100964 10.1016/j.cossms.2021.100964 34729031 Deshmukh S.P.; Patil S.M.; Mullani S.B.; Delekar S.D.; Silver nanoparticles as an effective disinfectant: A review. Mater Sci Eng C 2019,97,954-965 10.1016/j.msec.2018.12.102 30678983 Draz M.S.; Shafiee H.; Applications of gold nanoparticles in virus detection. Theranostics 2018,8(7),1985-2017 10.7150/thno.23856 29556369 Halfpenny K.C.; Wright D.W.; Nanoparticle detection of respiratory infection. Wiley Interdiscip Rev Nanomed Nanobiotechnol 2010,2(3),277-290 10.1002/wnan.83 20201109 Ai X.; Wang D.; Honko A.; Surface glycan modification of cellular nanosponges to promote SARS-CoV-2 inhibition. J Am Chem Soc 2021,143(42),17615-17621 10.1021/jacs.1c07798 34647745 Zhang Q.; Honko A.; Zhou J.; Cellular nanosponges inhibit SARS-CoV-2 infectivity. Nano Lett 2020,20(7),5570-5574 10.1021/acs.nanolett.0c02278 32551679 Horejs C.; From lipids to lipid nanoparticles to mRNA vaccines. Nat Rev Mater 2021,6(12),1075-1076 10.1038/s41578-021-00379-9 34567796 Gao C.; Wang Y.; mRNA metabolism in cardiac development and disease: Life after transcription. Physiol Rev 2020,100(2),673-694 10.1152/physrev.00007.2019 31751167 Fukushima Y.; Uchida S.; Imai H.; Treatment of ischemic neuronal death by introducing brain-derived neurotrophic factor mRNA using polyplex nanomicelle. Biomaterials 2021,270,120681 10.1016/j.biomaterials.2021.120681 33517206 Yang T.; Poenisch M.; Khanal R.; Therapeutic HNF4A mRNA attenuates liver fibrosis in a preclinical model. J Hepatol 2021,75(6),1420-1433 10.1016/j.jhep.2021.08.011 34453962 Cheng Q.; Wei T.; Farbiak L.; Johnson L.T.; Dilliard S.A.; Siegwart D.J.; Selective organ targeting (SORT) nanoparticles for tissue-specific mRNA delivery and CRISPR-Cas gene editing. Nat Nanotechnol 2020,15(4),313-320 10.1038/s41565-020-0669-6 32251383

Rights & Permissions Print Cite
Article Metrics
34
1
Wayfinder Image
Open Access Journals Promotions
© 2024 Bentham Science Publishers | Privacy Policy