Title:Prospection of Microfluidics for Local Drug Delivery
Volume: 23
Issue: 13
关键词:
微流体,局部药物输送,药物靶向,眼部输送,大脑输送,组织工程。
摘要: Significant endeavors can be made to develop effective drug delivery systems. Nowadays,
many of these novel systems have gained attention as they focus primarily on increasing the
bioavailability and bioaccessibility of several drugs to finally minimize the side effects, thus improving
the treatment's efficacy. Microfluidics systems are unquestionably a superior technology,
which is currently revolutionizing the current chemical and biological studies, providing diminutive
chip-scale devices that offer precise dosage, target-precise delivery, and controlled release. Microfluidic
systems have emerged as a promising delivery vehicle owing to their potential for defined
handling and transporting of small liquid quantities. The latest microfabrication developments have
been made for application to several biological systems. Here, we review the fundamentals of microfluidics
and their application for local drug delivery.