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Review Article

Prospection of Microfluidics for Local Drug Delivery

Author(s): Nimbagal R. Naveen*, Dornadula Girirajasekhar, Prakash S. Goudanavar, Chagaleti B. Kumar and Gunturu L. Narasimha

Volume 23, Issue 13, 2022

Published on: 05 August, 2022

Page: [1239 - 1251] Pages: 13

DOI: 10.2174/1389450123666220404154710

Price: $65

Abstract

Significant endeavors can be made to develop effective drug delivery systems. Nowadays, many of these novel systems have gained attention as they focus primarily on increasing the bioavailability and bioaccessibility of several drugs to finally minimize the side effects, thus improving the treatment's efficacy. Microfluidics systems are unquestionably a superior technology, which is currently revolutionizing the current chemical and biological studies, providing diminutive chip-scale devices that offer precise dosage, target-precise delivery, and controlled release. Microfluidic systems have emerged as a promising delivery vehicle owing to their potential for defined handling and transporting of small liquid quantities. The latest microfabrication developments have been made for application to several biological systems. Here, we review the fundamentals of microfluidics and their application for local drug delivery.

Keywords: Microfluidics, local drug delivery, drug targeting, ocular delivery, brain delivery, tissue engineering.

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