Title:Cellular and Molecular Mechanisms of Curcumin in Thyroid Gland
Disorders
Volume: 29
Issue: 16
关键词:
姜黄素,甲状腺,分子机制,激素,促甲状腺激素,垂体。
摘要: There is growing literature on the positive therapeutic potentials of curcumin.
Curcumin or diferuloylmethane is a polyphenol obtained from the plant Curcuma longa.
Curcumin is widely used in Ayurvedic and Chinese medicine for various conditions. The
role of curcumin in thyroid gland disorders has been demonstrated by its effects on various
biological pathways, including anti-inflammatory, antioxidant, anti-proliferative,
apoptosis, angiogenesis, cell cycle and metastasis. In this paper, we have reviewed the recent
literature on curcumin applications for thyroid dysfunction, including hyperthyroidism
and hypothyroidism, and discussed the molecular mechanisms of these effects.
This review aims to summarize the wealth of research related to the therapeutic effect of
curcumin on the thyroid gland.